Fisher John P., Mikos A.G., Bronzino J.D. (Eds.) Tissue Engineering

CRC Press, 2007. - 600 p.
ISBN-10:0-8493-9026-5
Increasingly viewed as the future of medicine, the field of tissue engineering is still in its infancy. As evidenced in both the scientific and popular press, there exists considerable excitement surrounding the strategy of regenerative medicine. To achieve its highest potential, a series of technological advances must be made.
Putting the numerous breakthroughs made in this field into a broad context, Tissue Engineering disseminates current thinking on the development of engineered tissues. Divided into three sections, the book covers the fundamentals of tissue engineering, enabling technologies, and tissue engineering applications. It examines the properties of stem cells, primary cells, growth factors, and extracellular matrix as well as their impact on the development of tissue engineered devices. Contributions focus on those strategies typically incorporated into tissue engineered devices or utilized in their development, including scaffolds, nanocomposites, bioreactors, drug delivery systems, and gene therapy techniques.
Finally, the book presents synthetic tissues and organs that are currently under development for regenerative medicine applications. The ability to engineer biocompatible tissue is the hallmark of modern biomedical engineering, integrating all aspects of every sub-discipline in the field. Featuring chapters drawn from the third edition of the best-selling Handbook of Biomedical Engineering as well as new contributions not found in the handbook, Tissue Engineering surveys the latest advances in this relatively young area. The contributing authors are a diverse group with backgrounds in academia, clinical medicine, and industry.
Furthermore, the text includes contributions from Europe, Asia, and North America, helping to broaden the views on the development and application of tissue engineered devicesContents
Fundamentals of Tissue Engineering
Fundamentals of Stem Cell Tissue Engineering
Growth Factors and Morphogens:Signals for Tissue Engineering
Extracellular Matrix: Structure, Function, and Applications to Tissue Engineering
Mechanical Forces on Cells
Cell Adhesion
Cell Migration
Inflammatory and Immune Responses to Tissue Engineered Devices
Enabling Technologies
Polymeric Scaffolds for Tissue Engineering Applications
Calcium Phosphate Ceramics for Bone Tissue Engineering
Biomimetic Materials
Nanocomposite Scaffolds for Tissue Engineering
Roles of Thermodynamic State and Molecular Mobility in Biopreservation
Drug Delivery
Gene Therapy
Tissue Engineering Bioreactors
Animal Models for Evaluation of Tissue-Engineered Orthopedic Implants
The Regulation of Engineered Tissues: Emerging Approaches
Tissue Engineering Applications
Bioengineering of Human Skin Substitutes
Nerve Regeneration: Tissue Engineering Strategies
Gene Therapy and Tissue Engineering Based on Muscle-Derived Stem Cells: Potential for Musculoskeletal Tissue Regeneration and Repair
Tissue Engineering Applications —Bone
Cartilage Tissue Engineering
Tissue Engineering of the Temporomandibular Joint
Engineering Smooth Muscle
Esophagus: A Tissue Engineering Challenge
Tissue Engineered Vascular Grafts
Cardiac Tissue Engineering: Matching Native Architecture and Function to Develop Safe and Efficient Therapy
Tissue Engineering of Heart Valves
Tissue Engineering, Stem Cells and Cloning for the Regeneration of Urologic Organs
Hepatic Tissue Engineering for Adjunct and Temporary Liver Support
Tissue Engineering of Renal Replacement Therapy
The Bioengineering of Dental Tissues
Tracheal Tissue Engineering,