CRC, 2010. - 662 pages.
Biopolymers found in marine animals and plants offer tremendous, largely untapped pharmaceutical potential. Research shows that these biopolymers can be used to combat various infectious as well as inflammatory, oxidative, and carcinogenic factors. Chitin, Chitosan, Oligosaccharides and Their Derivatives: Biological Activities and Applications covers the key aspects of these therapeutically valuable biopolymers and their derivatives, namely, their properties, sources, production, and applications in food science and technology as well as biological, biomedical, industrial, and agricultural fields.
Contains more than 100 Tables Figures and more than 800 References
Written by 40 international contributors who are leading experts in the field of natural biomaterials, this book pres an overview of the sources and production of chitin and chitosan derivatives. It also covers their:
Physical and chemical aspects Structural modifications for biomedical applications Biological activities, in particular, antimicrobial, anti-inflammatory, antioxidant, antihypertensive, anticancer, and antidiabetic activities Biomedical applications, including their possible implications as drug, vaccine, and gene carriers Industrial and agricultural applications
With their wide range of applications, the world is looking to biopolymers to serve as the basis for functional food- and drug development. This book is an important resource for those leading this effort.
Contents
The Sources and Production of Chitin and Chitosan Derivatives
Chitin and Chitosan from Terrestrial Organisms
Chitin and Chitosan from Marine Organisms
Chitin and Chitosan from Microorganisms
Enzymatic Production of Chitin from Crustacean Shell Waste
Continuous Production of Chitooligosaccharides by Enzymatic Hydrolysis
Biosynthesis of Cellulose–Chitosan Composite
Physical and Chemical Aspects of Chitin and Chitosan DerivativesChemical Derivatization of Chitosan for Plasmid DNA Delivery: Present and Future
X-Ray Diffraction Studies of Chitin, Chitosan, and Their Derivatives
Mechanical Properties of Chitosan and Chitosan–Poly(Vinyl Alcohol) Blend Films
Electrostatic Properties of Chitosan
Applications of Mass Spectrometry to Analyze Structure and Bioactivity of Chitooligosaccharides
The Use of Various Types of NMR and IR Spectroscopy for Structural Characterization of Chitin and Chitosan
Structural Modifications of Chitin and Chitosan DerivativesChemical Modifications of Chitosan Intended for Biomedical Applications
Enzymatic Modifications of Chitin and Chitosan
Biological Activities of Chitin and Chitosan DerivativesAntimicrobial Activity of Chitin, Chitosan, and Their Oligosaccharides
Anti-Inflammatory Activity of Chitin, Chitosan, and Their Derivatives
Chitosan Scaffolds for Bone Regeneration
Antioxidative Activity of Chitin, Chitosan, and Their Derivatives
Effects of Chitin, Chitosan, and Their Derivatives on Human Hemostasis
Antihypertensive Actions of Chitosan and Its Derivatives
Anticancer Activity and Therapeutic Applications of Chitosan Nanoparticles
Antidiabetic Activity and Cholesterol-Lowering Effect
Biomedical Applications of Chitin and Chitosan DerivativesChitin/Chitosan Oligosaccharides: Effective Substrates for Functional Analysis of Chitinases/Chitosanases
Low-Molecular-Weight Water-Soluble Chitosan with Free Amine Group for Drug Delivery
Chitosan/Chitosan Derivatives as Carriers and Immunoadjuvants in Vaccine Delivery
Chitosan-Conjugated DNA Nanoparticle Delivery Systems for Gene Therapy
Chitinolytic Enzymes from the Moderately Thermophilic Bacterium Ralstonia sp. A-471: Characterization and Application
Chitosan and Chitosan Derivatives as DNA and siRNA Carriers
Metabolic Pathway of Chitin and Its Oligosaccharides in Marine Bacterium Vibrios
Medical Applications of Chitin and Chitosan: Going Forward
Radiation Functionalization and Applications of Chitosan and Its Derivatives
Applications of Chitosan Oligosaccharide and Glucosamine in Dentistry
Applications of Chitosan and Its Derivatives in Veterinary Medicine
Industrial Applications of Chitin and Chitosan DerivativesSeparation Membranes from Chitin and Chitosan Derivatives
Hydrophobically Modified Acylated Chitosan Particles for Drug Delivery Applications: An Overview
Chitin, Chitosan, and Their Derivatives in Beverage Industry
Chitin Nanofibrils and Their Derivatives as Cosmeceuticals
Chitin, Chitosan, and Their Oligosaccharides in Food Industry
Chitin/Chitosan and Derivatives for Wastewater Treatment
Agricultural and Biotechnology Applications of Chitin and Chitosan and Their DerivativesChitin, Chitosan Derivatives Induced the Production of Secondary Metabolites and Plant Development through In Vitro and In Vivo Techniques
Mechanism and Application of Chitin/Chitosan and Their Derivatives in Plant Protection
Enhancing Crop Production with Chitosan and Its Derivatives