Nova Science Publishers, Inc. 2010. - 361 p.
Biochemistry is the organic chemistry of compounds and processes occurring in organisms. Histocytochemistry is the study of intracellular distribution of chemical, reaction sites, enzymes, etc. by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods. This book focuses on the role of norepinephrine in neuroinflammation, discusses the contribution of norepinephrine to Alzheimer's (AD) and Parkinson's Disease (PD) and provides an overview of potential therapeutical options targeting this neurotransmitter. Using methodologies such as questionnaires and laboratory tasks, experimental results showing specific effects related to noradrenaline in both clinical and experimental studies are described. This book also provides the current findings on the relationships between sympathetic nerve activity, B-adrenoceptor polymorphisms, and renal function. Recent methodologies that are useful for advanced immunohistochemistry (IHC) analysis in pathological research into therapeutic agents is also analyzed. Other chapters in this book discuss the unresolved areas of plasma cell research, an analysis of a new technology based on B-Cell targeting and its advantages over conventional methods for selective generation of novel monoclonal antibodies, as well as a review of the regulation of proteases and their role during the biocontrol process. Recent advances in the
isolation and characterization of glycosidases from hyperthermophilic microorganisms and the methods used for their application in oligosaccharide synthesis are explored as well.
Function of Norepinephrine in Neuroinflammation and Chronic Neurodegenerative DiseasesJohannes C.M. Schlachetzki, Antonio C. Pinheiro de Oliveira, and Bernd L. FiebichThe Role of Noradrenaline on Interpersonal FunctioningWai S. Tse and Alyson J. BondThe Neurotransmitter Norepinephrine and its Role in Affective DisordersEliyahu DremencovThe Role of Sympathetic Nerve Activity in Renal InjuryKazuko Masuo, Gavin W. Lambert and Murray D. EslerQuantitative Immunohistology - Problems and SolutionsAnthony S.Y. Leong and Trishe Y.M. LeongImmunohistochemical Basis for Orthodontic TreatmentToshiyuki Kawakam, Keisuke Nakano, Takako Shimizu, Takehiro Watanabe, Rina Muraoka, Akihiro Kimura and Hiromasa HasegawaPathological Research on Molecular-Targeted Therapy and Advanced Immunohistochemical ApproachesYutaka Hatanaka, Yuki Imaoka, Kaoru Hashizume, and Robert Y OsamuraPre-Embedding Scarce Biological Specimens for Light and Electron MicroscopyPhilippe TaupinRole of Surrogate Light Chain Expressing B Cells in the Formation of Self-Reactive AntibodiesPieter Fokko van Loo, Laurens P. Kil and Rudi W. HendriksUnique Enzymes of Aspergillus Fungi Used in Japanese BioindustriesEiji IchishimaExtracellular Proteases of Entomopathogenic FungiLóránt Hatvani, László Kredics, Sándor Kocsubé, László Manczinger, Csaba Vágvölgyi, Zsuzsanna AntalGlycoside Hydrolases from Hyperthermophiles: Structure, Function and Exploitation in Oligosaccharide SynthesisBeatrice Cobucci-Ponzano, Mosè Rossi and Marco MoracciStudies on the Thermal Stability of the Therapeutic Enzyme L-Asparaginase from Erwinia CarotovoraKaterina Lappa, Georgia A. Kotzia and Nikolaos E. LabrouExpert Commentary
A Novel Method for Generation of Monoclonal AntibodiesMasahiro Tomita