Annual Review of Pharmacology and Toxicology 2003 Volume 43

Файл содержит материалы, опубликованные в журнале "Annual Review of Pharmacology and Toxicology", Volume 43, 2003 г.
Induction of drug-metabolizing enzymes: a path to the discovery of multiple cytochromes P450
Protein flexibility and computer-aided drug design
Retinoid receptors and their coregulators
Novel pharmacological approaches to manage interstitial lung fibrosis in the twenty-first century
Nitric oxidereleasing drugs
2,5-hexanedione-induced testicular injury
Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts
Hormesis: the dose-response revolution
Signal transductiondirected cancer treatments
Regulatory mechanisms controlling gene expression mediated by the antioxidant response element
Monoamine transporters: from genes to behavior
Genetic polymorphisms of the human MDR1 drug transporter
Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
Trafficking of NMDA receptors
Telomere inhibition and telomere disruption as processes for drug targeting
Pharmacology and physiology of human adrenergic receptor polymorphisms
Gene therapy with viral vectors neeltje
K+ channel structure-activity relationships and mechanisms of drug-induced qt prolongation
Complementary and alternative therapeutics: rigorous research is needed to support claims
Challenging dogma: thresholds for genotoxic carcinogens? The case of vinyl acetate
The caenorhabditis elegans dopaminergic system: opportunities for insights into dopamine transport and neurodegeneration
Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics
Progress toward clinical application of the nitric oxidereleasing diazeniumdiolates
Innate immune responses to microbial poisons: discovery and function of the toll-like receptors
The role of drug transporters at the blood-brain barrier