Schecter A., Gasiewicz T.A. (Eds). Dioxins and health

2nd ed. — John Wiley & Sons, 2003. - 952 p.As science continues to appreciate the prevalence and power of dioxins, so it learns more about the harmful effects and effective preventive measures regarding these chemicals. Updating the acclaimed First Edition, Dioxins and Health, Second Edition covers the latest major scientific findings on the most potent, well known, and long-lasting of the persistent organic pollutants (POPS). The Second Edition reflects significant advances in dioxin research made in human epidemiology as well as in animal studies. Dioxins and structural analogues have been proven to cause immune alterations, nervous system effects, and cancer in humans, leading to its designation as a carcinogen by the World Health Organization. Endocrine alterations, caused by dioxins, have been shown to produce diabetes mellitus in adults and thyroid and sex hormone changes in newborns. The Second Edition reflects these new findings in a wide-ranging survey of these ubiquitous toxins. Toxicologists, environmental toxicologist epidemiologists, environmental chemists, regulators, and environmental attorneys will find Dioxins and Health, Second Edition to be an invaluable resource.Overview: The Dioxin Debate.
Production, Distribution, and Fate of Polychlorinated Dibenzo-p-Dioxins, Dibenzofurans, and Related Organohalogens in the Environment.
Dioxins and Dioxinlike PCBs in Food.
Toxicology of Dioxins and Dioxinlike Compounds.
Health Risk Characterization of Dioxins and Related Compounds.
Pharmacokinetics of Dioxins and Related Chemicals.
Dose–Response Modeling for 2,3,7,8-Tetrachlorodibenzo-p-Dioxin.
Immunotoxicology of Dioxins and Related Chemicals.
Developmental and Reproductive Toxicity of Dioxins and Related Chemicals.
Effects of Polychlorinated Biphenyls on Neuronal Signaling.
Experimental Toxicology: Carcinogenesis.
Ah Receptor: Involvement in Toxic Responses.
Biochemical Responses to Dioxins: Which Genes? Which Endpoints?
Evolutionary and Physiological Perspectives on Ah Receptor Function and Dioxin Toxicity.
Dioxin Toxicity and Aryl Hydrocarbon Receptor Signaling in Fish.
Exposure Assessment: Measurement of Dioxins and Related Chemicals in Human Tissues.
Human Health Effects of Polychlorinated Biphenyls.
Epidemiological Studies on Cancer and Exposure to Dioxins and Related Compounds.
Reproductive and Developmental Epidemiology of Dioxins.
Health Consequences of the Seveso, Italy, Accident.
The Yusho Rice Oil Poisoning Incident.
The Yucheng Rice Oil Poisoning Incident.