Williams P.L., James R.C., Roberts S.M. Principles of toxicology: environmental and industrial applications

2 th edit. - John Wiley & Sons, 2000. - 603 p.A fully updated and expanded edition of the bestselling guide on toxicology and its practical application. The field of toxicology has grown enormously since Industrial Toxicology: Safety and Health Applications in the Workplace was first published in 1985. And while the original edition was hugely popular among occupational health professionals, the time is ripe to address toxic agents not only in the industrial setting but also in the environment at large. Renamed Principles of Toxicology: Environmental and Industrial Applications, this new edition provides health protection professionals as well as environmental scientists with precise, up-to-date, practical information on how to apply the science of toxicology in both the occupational and environmental setting.Сonceptual aspects.
General Principles of Absorption, Distribution, and Elimination of Toxic Agents.
Biotransformation: A Balance between Bioactivation and Detoxification.
Hematotoxicity: Chemically Induced Toxicity of the Blood.
Hepatotoxicity: Toxic Effects on the.
Nephrotoxicity: Toxic Responses of the Kidney.
Neurotoxicity: Toxic Responses of the Nervous System.
Dermal and Ocular Toxicology: Toxic Effects of the Skin and Eyes.
Pulmonotoxicity: Toxic Effects in the Lung.
Immunotoxicity: Toxic Effects on the Immune System.
Specific areas of concern.
Reproductive Toxicology.
Mutagenesis and Genetic Toxicology.
Chemical Carcinogenesis.
Properties and Effects of Metals.
Properties and Effects of Pesticides.
Properties and Effects of Organic Solvents.
Properties and Effects of Natural Toxins and Venoms.
Applications.
Risk Assessment.
Example of Risk Assessment Applications.
Occupational and Environmental Health.
Epidemiologic Issues in Occupational and Environmental Health.
Controlling Occupational and Environmental Health Hazards.