Mount D., Pollak M. Molecular and Genetic Basis of Renal Disease: A Companion to Brenner and Rector's The Kidney

Philadelphia: W. B. Saunders, Inc., an affiliate of Elsevier, 2008. - 579 p. ISBN: 1416002529This companion to Brenner and Rector's The Kidney offers a state-of-the-art summary of the most recent advances in renal genetics. Molecular and Genetic Basis for Renal Disease provides the nephrologist with a comprehensive look at modern investigative tools in nephrology research today, and reviews the molecular pathophysiology of the nephron as well as the most common genetic and acquired renal diseases. A comprehensive clinical review of Medelian renal disease is also be included.
Detailed review of the molecular anatomy and pathophysiology of the nephron that provides relevant basic science to consider when diagnosing and managing patients with these disorders.The Tools of Molecular Nephrology
The impact of Genetics and Genomics on Renal Science and Renal Medicine
Manipulation of the Mouse Genome: Studying Renal Function and Disease
Cardiorenal Physiology of the Mouse: From Loss of Genome to Gain of Phenome
Murine Modeling of Kidney Development
Genetic Disorders of Renal Growth and Structure
Hereditary Disorders of Renal and Urogenital Development,
Autosomal Polycystic Kidney Disease (ADPKD)
Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Pathogenesis of Nephronophthisis and Medullary Cystic Kidney Disease
Genetic Disorders of Renal Function
Hereditary Nephroses
Molecular and Genetic Basis of Alport Syndrome
Nail-Patella Syndrome
Primary Hyperoxalurias: Molecular and Clinical Insights
Fabry Disease
Hereditary Disorders of the Proximal Tubule
Hereditary Disorders of the Thick Ascending Limb and Distal Convoluted Tubule
Hereditary Disorders of Distal Nephron Sodium and Potassium Transport
Hereditary Renal Tubular Acidosis
Hereditary Causes of Nephrogenic Diabetes Insipidus
Genetic Disorders of Calcium and Phosphate Homeostasis
Genetics and Renal Pathophysiology of Essential Hypertension
Acquired and Polygenic Renal Disease
Molecular Mechanisms of Proteinuria
Diabetic Nephropathy
Pathogenesis of HIV-Associated Nephropathy
Pathogenesis of Paraproteinemic Renal Disease
Preeclampsia
Molecular Insights into the Thrombotic Microangiopathies
IgA nephropathy
Glomerulonephritis Caused by Antineutrophil Cytoplasmic autoantibodies (ANCA)
Systemic Lupus erythematosus and the Kidney
Acute Tubular Necrosis