Boas U., Christensen J.B., Heegaard P.M.H. Dendrimers in Medicine and Biotechnology: New Molecular Tools

The Royal Society of Chemistry, 2006. - 191 p.
Dendrimers are a new class of macromolecule increasingly used in the fields of synthetic organic chemistry, biology, medicine and biotechnology. Using an interdisciplinary approach with particular emphasis on biological applications, Dendrimers in Medicine and Biotechnology: New Molecular Tools discusses the relationship between the dendrimer molecular motif and its biological properties. Throughout the book, examples from current research are provided.Contents
Dendrimers: Design, synthesis and chemical propertiesTerms and nomenclature in dendrimer chemistry
Dendrimer design
Dendrimer synthesis
Physicochemical properties of dendrimersProperties of dendrimers in biological systems
Significance of multivalent binding in biological interactions
Biocompatibility of dendrimersDendrimers as drug delivery devicesDendrimer hosts
Covalently bound dendrimer conjugates
Dendrimers as gene transfer reagentsDendrimer drugsAntiviral dendrimers
Antibacterial dendrimers
Dendrimers in antitumor therapy
Dendrimer in therapy of other diseases
Dendrimer based vaccines
Dendrimer interactions with proteins. Solubilisation of protein aggregatesDendrimers in diagnostics
Contrast agents based on dendrimers
Fluorescence enhanced by dendrimers
Dendrimers in bioassaysDendrimers as biomimicsDeddrimers as protein mimics
Dendrimers as artificial enzymes
Dendrimers as artificial antigens, antibodies and cell surfaces