Clement C.H. (Ed.) ICRP Statement on Tissue Reactions and Early and Late Effects of Radiation in Normal Tissues and Organs - Threshold Doses for Tissue Reactions in a Radiation Protection Contex

ICRP Publication
118. Elsevier, 2012. - 322 p.The aim of this report is to review the tissue and health effects of ionising radiation, with particular reference to their implications for dose limits in radiation protection, and for assessing health risks after accidental or therapeutic exposure. The report was prepared by a Task Group of ICRP Committee 1 under the following terms of reference: to review and evaluate the literature on the non-cancerous effects of ionising radiation on normal tissues, both in the context of high doses received by cancer patients treated with radiotherapy or in accidents, and lower doses sustained during accidental or occupational exposures, or during other incidents of unknown magnitude. This report updates the information given in Publication 41 (ICRP, 1984), including new data on cardiovascular effects and the risk of radiation-induced cataracts (Section 2). The influence of potential modifiers of the basic radiation sensitivity of normal tissues will also be considered with respect to compounds that either exacerbate and increase, or ameliorate and reduce, radiation injury (Section 3).