Hanson G., Berliner L. (ed.). High Resolution EPR. Applications to Metalloenzymes and Metals in Medicine. (Biological Magnetic Resonance, Volume 28)

Springer Science+Business Media, LLC 2009. - 670 p.This volume, High-Resolution EPR: Applications to Metal-loenzymes and Metals in Medicine, covers high-resolution EPR methods, iron proteins, nickel and copper enzymes, and metals in medicine. An eloquent synopsis of each chapter is provided by John Pilbrow in the Introduction which follows.This volume was conceived in 2005 at the Rocky Mountain Conference on Analytical Chemistry (EPR Symposium) to highlight the importance of high-resolution EPR spectroscopy to the structural (geometric and electronic) characterization of redox active cofactors in metalloproteins. We have been fortunate to have enlisted internationally recognized experts in this joint venture to provide the scientific community with an overview of high-resolution EPR and its application to metals in biology. This volume, High-Resolution EPR: Applications to Metalloenzymes and Metals in Medicine, covers high-resolution EPR methods, iron proteins, nickel and copper enzymes, and metals in medicine. An eloquent synopsis of each chapter is provided by John Pilbrow in the Introduction which follows.
A second volume, Metals in Biology: Applications of High-Resolution EPR to Metalloenzymes, will appear later this year covering the complement of other metalloproteins.High-Resolution EPR Methods
Advanced Pulse EPR Methods for the Characterization of Metalloproteins
Probing Structural and Electronic Parameters in Randomly Oriented Metalloproteins by Orientation-Selective ENDOR Spectroscopy
Molecular Sophe: An Integrated Approach to the Structural Characterization of Metalloproteins: The Next Generation of Computer Simulation Software
Spin-Hamiltonian Parameters from First Principle Calculations: Theory and Application
Iron Proteins
EPR of Mononuclear Non-Heme Iron Proteins
Binuclear Non-Heme Iron Enzymes
Probing the Structure-Function Relationship of Heme Proteins Using Multifrequency Pulse EPR Techniques
EPR Studies of the Chemical Dynamics of NO and Hemoglobin Interactions
Nickel and Copper Enzymes
EPR Investigation of [NiFe] Hydrogenases
Unique Spectroscopic Features and Electronic Structures of Copper Proteins: Relation to Reactivity
Metals in Medicine
Insulin-Enhancing Vanadium Pharmaceuticals: The Role of Electron Paramagnetic Resonance Methods in the Evaluation of Antidiabetic Potential
Chromium in Cancer and Dietary Supplements
High-Frequency EPR and ENDOR Characterization of MRI Contrast Agents
Conclusions